Wasaga Beach fire crews spent the night at a house fire on Lyons Court - not far from the roundabout on Mosley Street at Beachwood Road.
The call about the fire came in just before midnight (11:30 P.M. Wednesday).
Fire officials say no one was home at the time of the fire.
The house, which the Wasaga Beach Fire Department says is a complete loss, was home to a family of four.
They do have insurance and are staying with relatives in the area.
The investigation continues and the fire is not considered suspicious.
There is no dollar value of the damage yet.