Five people were taken to hospital after a two vehicle head-on crash on Highway 21 in Huron Township.
It happened about 6:15 PM on Wednesday when an Infinity QX4 SUV crossed the centre line and collided with a BMW 325i.
Two people in the Infiniti and three in the BMW were taken to hospital for treatment of non life threatening injuries.
South Bruce OPP, Bruce County EMS and the Ripley-Huron fire department all responded to the crash.
The cause of the crash remains under investigation.
No names have been released.
South Bruce OPP ask anyone who witnessed the collision to call them or Crime Stoppers.