The unemployment level in the area rose nearly half a percent to 4.9 percent in March.
Figures released by the Four County Labour Market Planning Board show fewer people working agriculture, and construction, but there were increases in Manufacturing and Utilities.
The board covers from Tobermory to Stratford and includes Grey, Bruce, Huron and Perth counties.
Executive Director Gemma Mendez-Smith while the number of people looking for work rose .4 percent in March, employers in the region still have jobs that are going unfilled.
She says those who have lost jobs can use employment services to help transition into new of different employment.
Meanwhile, the provincial jobless rate was unchanged in March.
Ontario employment rose by 10,600 jobs but the level of unemployment was steady at 5.5 percent, which is the lowest level since July of 2000.